روش جدید تشخیص هیپرترمی بدخیم با استفاده از پلاکت‌ها

ABSTRACT The malignant hyperthermia is recognized as one of the causes of anesthesia related death and is pharmacogenetic because both an abnormal gene and environmental factor are necessary. The basic diagnostic procedure is based on the measurement of ATP in patient specimen by ATP photometer.Platelets are used for the new diagnostic laboratory procedure in this study. Three individuals with abnormal gene and 20 people with normal one as control were selected in the state of Texas in United States of America. The experiment showed that halothane decreases the level of ATP in individuals with malignant hyperthermia . Halothane may show little inhibition on normal people.The results of this study show that platelets worked out well and do not have those limitations of the previous procedure.